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diagnosis clinical differential msk sports injection physicalexam corticosteroid intraarticular knee anemia management causes lateral medial algorithm blood classification dermatology hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
uremic syndrome (HUS ... cold agglutin disease ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections ... differential #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic ... SLE) - Viral infections ... APLS • Acute Infectious ... Differential #Diagnosis #hematology ... #rheumatology #
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell disease ... DIC, TTP, HELLP, HUS ... inclusions - If infection ... Algorithm #workup #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... Diaqnoses: • Infectious ... borrelia, Rubeola, HBV ... Coxsackie, CMV, EBV, HIV ... management #treatment #rheumatology
Medial Approach Knee Intra-articular Corticosteroid Injection Landmark 1/3 to 1/2 way from top of patella. Find
Corticosteroid Injection ... #clinical #video ... #physicalexam #procedure ... #msk #orthopedics ... #sports #rheumatology
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 Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Causes: • Liver disease ... drug induced • Infections ... • MAHA: TTP, HUS ... classification #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... - MAHA: TTP, HUS ... , Drugs, Liver Disease ... Internal (RBC) - Infections ... Differential #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Due to Viral infection ... Diagnosis: • hemolytic ... Mycoplasma, EBV, HIV ... #hemolytic #anemia ... #hematology #diagnosis
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
chronic liver disease ... hemochromatosis, hemolytic ... anemia, CKD, hiv ... Diseases Fellowship ... #dermatology #legs
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
menstrual - Recent procedures ... - Infection exposure ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... Causes #Workup #hematology
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