16 results
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Chemotherapy • Infectious ... : HIV, Hepatitis ... CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... diagnosis #causes #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... response preceding infection ... Campylobacter jejuni - HIV ... of intrathecal spinal ... management #treatment #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... immunodeficiency virus (HIV ... transplantation CLINICAL ... #Syndrome #diagnosis ... #management #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
epidural hematoma • infections ... cord infarct • HIV ... infection/abscess ... cord • Guillain-Barre ... diagnosis #causes #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... Infections: - ... Viral: VZV, HSV, ... HIV, CMV, HTLV ... disorders #diagnosis #neurology
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... with pulmonary TB ... #differential #TB ... #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
Syndromes Spinal ... result in permanent neurologic ... Infarction - Infection ... syphilis, and HIV ... differential #diagnosis #neurology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... , HIV) • Glucocorticoid
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- CMV - HCV ... - HIV • Immune ... and thymoma DDX ... immunodeficiency virus (HIV ... CMV) • Epstein-Barr
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
early stages of infection ... Clinical Presentation ... : The clinical ... syndrome of HAD ... dementia #AIDS #Neurology