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hematology differential erythematosus sle algorithm arterial associations cerebritis cns cryofibrinogenemia hypercoagulable management monoclonal neurology oncology paraproteinemias pathophysiology phenomenon reynaud table
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... , others (RNP, aPL ... antibodies) • Antiphospholipid ... • Scleroderma (Systemic ... diagnosis #associations
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Hyperviscosity, TTP, APLS ... • Nephrotic Syndrome ... Malignancy - Antiphospholipid ... antibodies (APLS
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... the formation of autoantibodies ... vasculopathy, thrombosis ... (for secondary APS ... CNS #neurology #rheumatology
Raynaud Phenomenon Differential Diagnosis: Rheumatologic - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD Heme -
: Rheumatologic ... - MCC systemic ... Hypercoagulable state (eg APLA ... ) - Vascular: embolic ... / thrombotic, vasospasm
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Anti-Ro/SSA autoantibodies ... Differential Diagnosis ... Non-autoimmune rheumatologic ... #Diagnosis #Rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid ... Syndrome (APLS) ... Hypercoagulable Workup ... excluded Testing: • Lupus ... #diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Organomegaly+↑RBC/plt+, ↑thrombosis ... macular Vasculitis) Autoantibodies ... to cold IgG • Lupus ... Hyperviscosity (Thrombosis ... #Differential #Diagnosis
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
processes: • Systemic ... HUS and HIT • Antiphospholipid ... syndrome • Warfarin-induced ... DIC • Septic emboli ... #rheumatology #
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