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algorithm champs complement cryofibrinogenemia framework hypercoagulable hypocomplementemia joint low mnemonic nonpalpable pain palpable pathophysiology platelets purpura rashes skin thrombocytopenia thrombocytosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Diagnosis Framework ... • Nephrotic Syndrome ... Arterial Embolism ... Malignancy - Antiphospholipid ... pathophysiology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... • Inflammatory Conditions ... Kawasaki, Nephrotic syndrome ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - PNH - APLS ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... syndrome, atheroembolic ... CHAMPS #Mnemonic #diagnosis ... #differential # ... hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... syndrome • Vasculitis ... • Cholesterol emboli ... Sarcoidosis #dermatology ... #diagnosis #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... Autoimmune: SLE, RA, antiphospholipid ... syndrome - Pregnancy ... #hematology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid ... Syndrome (APLS) ... clinical episodes of arterial ... maternal chromosomal causes ... #diagnosis #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulins • Negative causes ... HUS and HIT • Antiphospholipid ... syndrome • Warfarin-induced ... #rheumatology # ... hematology
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