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diagnosis algorithm thrombocytopenia anticoagulation arterial breakthrough champs complement dvt dyspnea embolism framework gap globulin hypercoagulable hypocomplementemia low mds mnemonic myelodysplasia
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... RA, Sjogren's), antiphospholipid ... syndrome, atheroembolic ... subacute bacterial endocarditis ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Autoimmune: SLE, RA, antiphospholipid ... syndrome - Pregnancy ... valve replacement, endocarditis ... Diagnosis #Framework #hematology
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
Behcet's disease - APLS ... Structural - Pelvic masses ... - May-Thurner syndrome ... anticoagulation #hematology ... #differential #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- PNH - APLS ... • Bacterial endocarditis ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... SLE • CLL • APLA ... Non-lmmune: • HELLP Syndrome ... #Hematology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Dyspnea - Differential ... Hepatopulmonary syndrome ... Guillain Barre - ALS ... Transverse myelitis • Hematology ... #dyspnea #sob #differential
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... Malignancy - Antiphospholipid ... antibodies (APLS ... pathophysiology #hematology ... #differential #
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid ... Syndrome (APLS) ... Hypercoagulable Workup ... maternal chromosomal causes ... #diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Schonlein Purpura - Endocarditis ... Rash: - ITP - APLS ... deficiency Work ... #dermatology #physicalexam
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... Workup: • Complete ... blood count with differential ... #diagnosis #hematology
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