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diagnosis classification differential allergy associations hypersensitivity management patterns sle types anca antineutrophil arthritis druginduced igg4 laboratory pathophysiology phenotypes related testing
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Rheumatic Diseases ... lupus erythematosus ... lupus erythematosus ... • Rheumatic Diseases
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic ... Diseases: • Homogeneous ... connective tissue disease ... lupus erythematosus ... #Antibodies #ANA
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ANA ... others (RNP, aPL antibodies ... ribonucleoprotein) • RA: Rheumatoid ... • Scleroderma (Systemic ... #associations #table
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... their Disease Associations ... ANA - Non-specific ... hepatitis Anti-CCP, Rheumatoid ... antibodies
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... connective tissue disease ... #Antinuclear #Antibody ... diseases
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Decade Skin Disease ... vasculitis, rheumatoid ... tissue disease ... diseases (i.e.
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Association with disease ... with auto-immune diseases ... #table #ANA
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Action: IgG/lgM antibodies ... , Haemolytic disease ... days - Examples: Rheumatoid ... lupus erythematosus ... classification #comparison
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Diseases • Septic ... lupus erythematosus ... connective-tissue disease ... #Disease #Rheumatoid
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... during hemolytic disease ... glomerulonephritis, rheumatoid ... systemic lupus erythematosus ... #Table
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