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diagnosis antinuclear hematology lupus sle vasculitis classification management pain patterns table anca antibody antineutrophil aortitis autoimmune cardiology causes chronic comparison
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... Juvenile Idiopathic Arthritis ... SLE), Sjogren's Syndrome ... #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Disease! ... Rheumatic Diseases ... • Rheumatic Diseases ... #rheumatology #diagnosis ... #differential
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
temporalis (giant-cell ... - Kawasaki disease ... infectious diseases ... lupus erythematosus ... Vessels #Diagnosis #Rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
, Cogan's Syndrome ... polychondritis, Behcet's Disease ... ) • Rheumatic Diseases ... : IgG4-Related Disease ... (RA), Systemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... tissue disease ... diseases (i.e. ... (e.g. thyroid disease ... ) • Kikuchi disease
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... : - ANA 95-100% ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
IBD, Whipple's disease ... • Whipple's disease ... - Whipple's disease ... #joint #pain #differential ... #diagnosis #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
erythematosus ... cases • Sjögren syndrome ... connective tissue disease ... 90% • Anti-GBM disease ... #diseases
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pain • Kawasaki Disease ... (Granulomatous disease ... rheumatic diseases ... atherosclerotic disease ... most important diseases
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Heavy Chain disease ... Evans • ITP • Cl-NH ... Sneddon-Wilkinson disease ... #Diagnosis #Oncology
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