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diagnosis antinuclear classification patterns signs algorithm anca antibody antineutrophil aortitis arthropathies arthropathy causes comparison cryoglobulinemia cryoglobulins disorders druginduced hematology joint
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Diseases: • Homogeneous ... tissue disease ... lupus erythematosus ... lupus erythematosus ... (SLE), Systemic
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Rheumatic Diseases ... lupus erythematosus ... lupus erythematosus ... • Rheumatic Diseases ... : Lupus (SLE), Systemic
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
polychondritis, Behcet's Disease ... Diseases: IgG4- ... Related Disease ... Systemic lupus ... erythematosus (SLE
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... vasculitis, rheumatoid ... Still disease, ... diseases (i.e. ... #Systemic #Lupus
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Diagnosis and Lupus ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... #Systemic #Lupus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... pain (20%) Renal disease ... #SLE #systemic ... #erythematosus # ... signs #symptoms
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... erythematosus ... connective tissue disease ... 90% • Anti-GBM disease ... #diseases
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Inflammatory Bowel Disease ... Arthropathy with Crohn’s Disease ... autoimmune disease ... Lupus - with Systemic ... Lupus Erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
(Granulomatous disease ... rheumatic diseases ... lupus erythematosus ... atherosclerotic disease ... , and SLE) • Urinalysis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
, Arthritis, myalgia ... of autoantibodies ... Lupus Erythematosus ... Evolution: Chronic disease ... #table #rheumatology
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