15 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and ... their Disease Associations ... ANA - Non-specific ... (TTG) - Celiac disease ... antibodies
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Rheumatology • ... others (RNP, aPL antibodies ... • Scleroderma (Systemic ... #associations #table
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antibody) and ANCA ... connective tissue disease ... 90% • Anti-GBM disease ... #rheumatology # ... diseases
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antibody refers ... Disease! ... Rheumatic Diseases ... • Rheumatic Diseases ... #rheumatology #diagnosis
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... female, asian • Systemic ... (antinuclear antibodies ... #Related #Disease ... #treatment #rheumatology
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
Tests for Celiac Disease ... patients with celiac disease ... Sensitivity for celiac disease ... value for celiac disease ... #Table
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Allergen-specific lgE antibodies ... - Local and systemic ... during hemolytic disease ... Type Ill - IgG and ... Diagnosis #Reactions #Table
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Association with disease ... with auto-immune diseases ... #table #ANA
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... tissue disease ... diseases (i.e. ... (e.g. thyroid disease ... ) • Kikuchi disease
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... macular Vasculitis) Autoantibodies ... Evans • ITP • Cl-NH ... anemia due to cold IgG ... Sneddon-Wilkinson disease