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differential antibodies associations classification management aortitis comparison conditions cryoglobulinemia cryoglobulins druginduced erythematosus joint pain patterns phenotypes related testing treatment types
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
(rare) • Rheumatic ... Diseases: IgG4- ... (IgG4-RD), Rheumatoid ... Systemic lupus ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Rheumatic Diseases ... • Rheumatic Diseases ... : Lupus (SLE), Systemic ... • Non-Rheumatic ... #patterns #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • ... Lupus (SLE): ANA ... ribonucleoprotein) • RA: Rheumatoid ... Ill • ANCA Vasculitis ... #Rheumatology #
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... hepatitis Anti-CCP, Rheumatoid ... c-ANCA - Vasculitis ... #diagnosis #table ... #rheumatology #
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Rheumatic ... Rheumatic fever ... stenosis - Rheumatic ... endocarditis, Rheumatic ... #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... (SLE) - Antinuclear ... #Disease #Rheumatoid ... #workup #diagnosis ... #testing #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... fever) and laboratory ... vasculitis, rheumatoid ... #Systemic #Lupus ... #Rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... female, asian • Systemic ... , rheumatoid factor ... #Related #Disease ... #treatment #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... respectively, having rheumatoid ... Elevated serum rheumatoid ... (SLE), rheumatoid ... classification #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
95% (IgG anti-chromatin ... of autoantibodies ... • Evolution: Chronic ... disease Dr. ... #table #rheumatology
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