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diagnosis antibodies antinuclear table antibody antineutrophil aortitis bee cryoglobulinemia cryoglobulins hematology inflammatory management monoclonal myopathy myositis neurology oncology paraproteinemias size
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... their Disease Associations ... ANA - Non-specific ... c-ANCA - Vasculitis ... granulomatosis p-ANCA
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... : The ANA patterns ... lupus erythematosus ... lupus erythematosus ... #patterns #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic Diseases ... lupus erythematosus ... connective tissue disease ... #patterns #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... - Kawasaki disease ... small vessels - ANCA-associated ... lupus erythematosus ... #Diagnosis #Rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
lupus erythematosus ... connective tissue disease ... 90% • Anti-GBM disease ... Jcortesizaguirr #ANA ... #diseases
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
(Granulomatous disease ... rheumatic diseases ... lupus erythematosus ... atherosclerotic disease ... most important diseases
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
less common diseases ... Vogt-Koyanagi-Harada (VKH) disease ... • Systemic lupus ... polychondritis • Behcet disease ... spectrum disorder • ANCA-associated
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Decade Skin Disease ... tissue disease ... rheumatologic diseases ... antibodies • (-) ANA
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
polychondritis, Behcet's Disease ... Nodosa (PAN), ANCA ... ) • Rheumatic Diseases ... : IgG4-Related Disease ... lupus erythematosus
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus ... with disease activity ... searched for when ANA ... with auto-immune diseases ... #table #ANA
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