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differential ana antinuclear erythematosus table management vasculitis antibody antineutrophil arthritis associations autoimmune classification comparison disease druginduced hematology laboratory leukemia lymphocytic
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Lupus (SLE): ANA ... others (RNP, aPL antibodies ... • Scleroderma (Systemic ... diagnosis #associations
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... in drug-induced SLE ... ) • Systemic sclerosis ... cases • Sjögren syndrome ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... Syndrome (SS), ... (SLE), Systemic ... : Lupus (SLE), Systemic ... #rheumatology #diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Auto-Antibodies ... #Systemic #Lupus ... #autoantibodies ... #signs #symptoms
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
months to years) Systemic ... • Evolution: Chronic ... disease Dr. ... #table #rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Anti-Ro/SSA autoantibodies ... : • Symptoms limited ... : • Chronic B-cell ... #Systemic #Lupus
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... overlap syndromes ... #Systemic #lupus ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
as systemic lupus ... Symptoms (Sx) in ... purpura: strong sign ... vasculitis, and SLE ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... #workup #oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
as SLE, atherosclerotic ... Symptoms (SX) in ... purpura: Strong sign ... Eosinophilia, asthma, chronic ... #Rheumatology
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