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diagnosis erythematosus sle antinuclear antibodies associations autoimmune classification comparison druginduced hematology management mimickers monoclonal myopathy myositis oncology paraproteinemias patterns signs
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ANA ... • Scleroderma (Systemic ... : P-ANCA (perinuclear ... ), C-ANCA (cytoplasmic ... #associations #table
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... arteritis, Cogan's Syndrome ... Nodosa (PAN), ANCA ... Arthritis (RA), Systemic ... lupus erythematosus
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
) ANA or Anti-NucIear ... context of other symptoms ... : Lupus (SLE), Systemic ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Auto-Antibodies: - ANA ... Diagnosis and Lupus ... #signs #symptoms ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Others: • Lupus ... Symptoms (Sx) in ... claudication, aortitis ... LFT • ESR • ANA ... #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
: - ANA > ... of autoantibodies ... : - ANA > ... sle #comparison #table ... #rheumatology #
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus ... searched for when ANA ... SLE-SSc-AlM overlap syndromes ... #Systemic #lupus ... #table #ANA
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... Diagnosis: • ANCA-associated ... : • Symptoms limited ... antibodies • (-) ANA
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... macular Vasculitis) Autoantibodies ... Evans • ITP • Cl-NH ... to cold IgG • Lupus ... #Monoclonal #Differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
• Anti-NXP2 (ANA ... -1 antibodies (ANA ... or head drop • ANA ... Mechanic's hands Autoantibodies ... • Conduction system
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