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diagnosis differential lupus ana antinuclear vasculitis antibodies classification management patterns table antibody antineutrophil aortitis autoimmune cll comparison cryoglobulinemia cryoglobulins druginduced
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... tissue disease ... Juvenile Idiopathic Arthritis ... Syndrome (SS), ... (SLE), Systemic
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Disease! ... tissue disease ... (SLE), Systemic ... : Lupus (SLE), Systemic ... #patterns #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
- Kawasaki disease ... small vessels - ANCA-associated ... lupus erythematosus ... induced by chronic ... Vessels #Diagnosis #Rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
lupus erythematosus ... in drug-induced SLE ... connective tissue disease ... 90% • Anti-GBM disease ... #diseases
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Decade Skin Disease ... diseases (i.e. ... (e.g. thyroid disease ... ) • Kikuchi disease
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
, Cogan's Syndrome ... polychondritis, Behcet's Disease ... ) • Rheumatic Diseases ... : IgG4-Related Disease ... (RA), Systemic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... • Evolution: Chronic ... disease Dr. ... Management #Summary #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... #Diagnosis #autoantibodies
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pain • Kawasaki Disease ... (Granulomatous disease ... rheumatic diseases ... atherosclerotic disease ... most important diseases
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... months to years) Systemic ... Lupus Erythematosus ... • Evolution: Chronic ... disease Dr.
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