11 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... life-threatening • Treatment ... • Evolution: ... #Erythematosus
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... permeability Diagnosis ... #Erythematosus ... #SLE #CNS #neurology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... #Systemic #Lupus ... #Erythematosus ... #SLE #Summary #diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Erythematosus ( ... life-threatening • Treatment ... • Evolution: ... #rheumatology #diagnosis
Lyme Disease: Clinical diagnosis. Likely if recent hiking, travel to endemic area, erythema migrans (EM), an
Disease: Clinical diagnosis ... migrans (EM), an erythematous ... patch that blanches ... Treatment is doxycycline ... carditis, meningitis (see
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus ... erythematosus [ ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Induced Systemic Lupus ... Erythematosus ... with drug-induced SLE ... for 1 year of treatment ... #differential #diagnosis
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
GBS), systemic lupus ... erythematosus ( ... SLE), polymyositis ... Atorvastatin Diagnosis ... toxicity #myopathy #diagnosis
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
are excellent at evaluating ... & Dry) is the treatment ... Cardiac cath if ... algorithm #management #cardiology ... #treatment #table
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... constitutional symptoms • Treatment ... cutaneous-DIL • Evolution ... #rheumatology #diagnosis ... #treatment #management