213 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
and Reduction in HbA1c ... Elevation == Decreased ... Elevation #Reduction #HbA1c ... #HgbA1c #Laboratory ... #Increase #Decrease
COMMONLY ENCOUNTERED MEDICATIONS THAT INCREASE OR DECREASE WARFARIN’S INTERNATIONAL NORMALIZED RATIO (INR)

#Pharmacology #Warfarin #Medications #Interactions #INR
MEDICATIONS THAT INCREASE ... OR DECREASE WARFARIN ... RATIO (INR) #Pharmacology ... INR #Increases #Decreases
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
• alpha 1 • Increase ... • Inotropy > Increase ... • Inotropy, Decrease ... • Inotropy, Decrease ... #criticalcare #pharmacology
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Cell Disease • Decreases ... 4.5 vs. 2.4) • Decreases ... organ benefit and decreased ... pathophysiology #pharmacology
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
Beta-Blockers • Decreases ... thyroid hormone • Decreases ... Steroids • Decrease ... ThyroidStorm #Management #Pharmacology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Excretion Decreased ... , Pentamidine Decreased ... Ketoconazole Decreased ... Beta-Blockers Decreased ... Pathophysiology #Pharmacology
Calcium Channel Blockers - Dihydropyridines vs Non-Dihydropyridines
Dihydropyridines (amlodipine, felodipine, nifedipine, nicardipine)
 • SVR: Decrease
 • Inotropy:
nicardipine) • SVR: Decrease ... verapamil) • SVR: Decrease ... • Inotropy: Decrease ... NonDihydropyridines #pharmacology
Pain mechanisms and analgesics pathways

#Pain #Pathways #Analgesics #Pharmacology #Tracts #Neurology
Pathways #Analgesics #Pharmacology ... #Tracts #Neurology
Fibrates - Gemfibrozil and Fenofibrate 
Mechanism: activates PPAR alpha
Lipid Effects:
 - Decrease TG by 30-50%
 -
Lipid Effects: - Decrease ... by 30-50% - Increase ... by 5-15% - Decrease ... #Fenofibrate #Pharmacology
Definitions of AKI, CKD, AKD
Acute Kidney Injury (AKI):
 • Increase in SCr by 2 50% within
Injury (AKI): • Increase ... 7 days, OR • Increase ... months, OR • Decrease ... GFR by ≥ 35% or increase ... #Definitions #nephrology