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diagnosis hematology causes workup @dharsaty anemias approach classification disease dm2 eas elevation evaluation false fructosamine glycatedproteins hemoglobina1c hgba1c incomplete increase
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
and Reduction in HbA1c ... blood loss • Hemolytic ... anemia • Splenomegaly ... Elevation #Reduction #HbA1c ... Diagnosis #DM2 #Differential
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... Decreased WBCs ... - Decreased/NormaI ... #Differential #
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential ... Diagnosis Algorithm ... Signs of anemia ... #Anemias #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... Hypochromic & microcytic RBCs ... #Anemia #Differential
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... Decreased RBC ... Classification #Approach #Differential ... #Diagnosis #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... without platelet decrease ... #Anemia #Differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... schistocytes, nucleated RBCs ... , and decreased ... anemia Indirect ... WBC count and differential
Hemoglobin A1c (glycated hemoglobin) reflects the average blood glucose concentration over the course of the RBC
correlated with 35-76% decrease ... span, such as hemolytic ... anemia or blood ... in sickle cell anemia ... test, such as anemia
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
Albumin ≤3.0 g/dL, anemia ... purposes of this algorithm ... lack of tapering, decreased ... clinical and lab signs ... #Diagnosis #Peds
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
dependent DM ACS ... event, follow ACC algorithm ... Cataract Plan for Meds ... are needed: • HgbA1c ... or death (CARP, DECREASE
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