28 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... coagulation (DIC) - HELLP ... lymphoproliferative disorders ... #hematology #anemia
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... TTP, HUS, DIC, HELLP ... udaygulati #Hemolytic ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... DIC/TTP/HUS - Hemolytic ... #Differential #Diagnosis ... #hematology #rheumatology ... #nonpalpable #dermatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... thrombocytopenia - DIC, TTP, HELLP ... Consider RBC membrane disorder ... #Differential #Diagnosis ... Algorithm #workup #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Pregnancy - TTP/HUS, HELLP ... (Hemolysis, Elevated ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential Diagnosis ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... #Differential #Diagnosis ... #Hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
(Hemolysis, Elevated ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... hematemesis, melena, heavy ... or if a primary hematologic ... #Differential #Diagnosis ... #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... #Causes #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Inherited Non-hemolytic ... without evidence of hemolysis ... and stress may cause ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology