14 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Lupus Erythematosus ... • Rheumatoid Arthritis ... Age > 50 • Chronic ... Algorithm #Causes #Hematology ... #Oncology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... Juvenile Idiopathic Arthritis ... lupus erythematosus ... scleroderma), Rheumatoid Arthritis ... Juvenile Idiopathic Arthritis
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... - Hemolytic anemia ... Diagnosis and Lupus ... #Lupus #Erythematosus
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... , inflammatory arthritis ... vasculitis, rheumatoid arthritis ... Arthritis: • ... : • Chronic B-cell
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Lupus Erythematosus ... Clinical Domains ... • Arthritis domain ... least 2 joints • Neurologic ... #Lupus #Erythematosus
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
juvenile idiopathic arthritis ... lupus erythematosus ... juvenile idiopathic arthritis ... lupus erythematosus ... Diagnosis #Management #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
of the joints (arthritis ... of the joints (arthritis ... Neutrophilic rheumatoid arthritis ... #diagnosis #dermatology ... #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... Glomerulonephritis, arthritis ... mucositis - Rash, arthritis ... lupus erythematosus ... purpura: strong sign
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
myocarditis, coronary arteritis ... SLE, Reactive arthritis ... Ocular melanoma • Arthritis ... SLE, Reactive Arthritis ... chronic arthritis-Azathioprine