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diagnosis transaminitis abscess algorithm chemistry children cholestatic dermatology dili drug embolism enzymes function gastroenterology hepatocellular idiosyncratic induced interpretation nonpalpable palpable
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... more specific for hepatic ... Transaminitis #diagnosis #differential ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... injury) • Ischemic ... ) • Non-hepatic ... Diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... #differential # ... Diagnosis #Management ... gastroenterology #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Thrombosis - Differential ... Syndrome, Ischemic Liver ... Hyperhomocysteinemia - Heparin-induced ... Vasculitis • Injury ... pathophysiology #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... replaced by non-hepatic ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... deficiency • Liver ... gangrenosum • Bacterial ... #Diagnosis #hematology
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
Pyogenic liver abscess ... children Common bacterial ... through: - Hepatic ... children #peds #differential ... #diagnosis #hepatology
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