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diagnosis transaminitis algorithm injury causes chemistry dili disease disorders drug function gap globulin hepatobiliary hepatocellular idiosyncratic induced interpretation liverenzymes management
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... Chronic Viral Hepatitis ... #Differential # ... Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... • Infections: Hepatitis ... #Diagnosis #hepatology ... Transaminitis #LFTs ... #hepatitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
hepatomegaly and anemia ... progressing to acute liver ... Liver transplant ... Hepatobiliary #hepatology ... #hepatitis #differential
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Check Acute viral hepatitis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
: INR/PT, aPTT(liver ... changes), high MCV anemia ... gastric bypass), LFT ... (liver disease) ... Causes #Workup #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Sarcoidosis) • Liver ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential ... #diagnosis #hematology
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