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diagnosis differential hematology management hemolytic algorithm anesthesia checklist classification disease extravascular hemolysis intraoperative intravascular vasculitis workup addisons adrenal agglutinin aids
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Diagnosis Algorithm Signs ... of anemia and hemolysis ... Immune-mediated Hemolysis ... : • Autoimmune ... Diagnosis #Algorithm #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... reticulocytes • Hemolysis ... 2) LOOK FOR a cause ... Warm #Antibody #Autoimmune ... management #treatment #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Microangiopathic hemolytic anemia ... idiopathic) - Autoimmune ... Extravascular #Causes ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Cold AIHA • Alloimmune ... immune-complex hemolytic anemia ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... iron deficiency, hemolysis ... disorders (e.g. autoimmune ... #hematology #secondary
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
suspected: • Signs ... and symptoms of ... Iron-deficiency anemia ... without discernable cause ... • Signs of osteoporosis
CLINICAL MANIFESTATIONS OF ADRENAL INSUFFICIENCY. Primary and secondary adrenal insufficiency: - Tiredness, weakness, mental depression
hypotension - Nausea ... mild normocytic anemia ... - Vitiligo - Autoimmune ... without marked anemia ... Insufficiency #Signs
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... • Compensated hemolysis ... CLL (older) • Autoimmune ... intravascular hemolysis ... #hematology #diagnosis
High Central Neuraxial Block - Guidelines for Crises in Anaesthesia • Can occur with deliberate or accidental
• Symptoms are ... Consider other causes ... that may mimic signs ... and symptoms, including ... Neuraxial #Block #Anesthesiology
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia If the patient is unconscious, signs of cardiac
Guidelines for Crises ... is unconscious, signs ... is conscious, symptoms ... calcium. ❽ Treat anaemia ... Ischemia #Ischaemia #Anesthesiology
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