41 results
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
Pulmonary: Cough, hemoptysis ... dysrhythmias • Ophthalmologic ... Sarcoidosis #Diagnosis #Symptoms ... #Signs #Pulmonary
Low O2 saturation that does not respond to supplemental O2
- Key diagnostic feature (sat < 85%
averaging by the pulse ... FiO2 Severity of symptoms ... pneumonia, COPD, anemia ... Concentrations #Signs ... #Symptoms
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... and symptoms: ... • Symptomatic anemia ... Complications: • Can
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... /Symptoms: - Fever ... - High serum CRP ... - Normocytic Anemia ... #Symptoms #Vasculitis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
of anemia include ... • hemolytic anemia ... • Compensated hemolysis ... intravascular hemolysis ... disease #hemolytic #anemia
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
• Cephalic symptoms ... Constitutional symptoms ... Increased ESR and/or CRP ... Doppler US : halo sign ... #Rheumatology #Ophthalmology
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
malaise • Rash (can ... testing • No symptoms ... Aortitis, thoracic aortic ... Syphilis #Stages #symptoms ... #signs #diagnosis
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
bloodstream Hemolysis ... • Hemolytic Anemias ... , PNH, immune hemolysis ... - Pernicious anemia ... associated with any symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Endocarditis, Aortic ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Risk Factors and Signs ... , Malnutrition Signs ... Haematological: Anaemia ... Peripheral neuropathy, Optic ... #riskfactors #symptoms