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hematology management differential oncology algorithm leukemia chronic cll infectiousdiseases lymphocytic abscess agglutinin aplastic arteritis ascorbicacid cancer cold disease erythematosus gca
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... ): • Acute infection ... malignancies • Anemia ... iron deficiency, hemolysis ... #Causes #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... blood loss, Acute hemolysis ... , deficiency anemia ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Myelofibrosis Infectious ... effect following treatment ... Iron deficiency anemia ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... • Bleeding • Hemolysis ... Inflammation, Chronic Infection ... #MCV #Classification ... #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Clinical Presentation ... anemia • Cold ... • Compensated hemolysis ... intravascular hemolysis ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... Complications: 1) Infection ... marrow failure with anemia ... #hemeonc #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... Treatment: ... • Improve the symptoms ... #diagnosis #management
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... Lung Abscess - Clinical ... Leukocytosis, anemia ... > 10 days - Hemoptysis ... #differential #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... basophilia, and thrombocytosis ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... vasculitis vs infection ... systemic complaints- anemia ... , thrombocytosis ... them, but urgent rheumatology
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