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diagnosis differential management rheumatology algorithm causes dermatology hepatology oncology gastroenterology anemia clinical nephrology skin table systemic pulmonary vasculitis classification comparison
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Hypereosinophilic Syndrome ... Hypereosinophilic Syndrome ... suspect underlying hematologic ... Diagnosis and Treatment ... #HES #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... cold agglutin disease ... e.g. sickle cell disease ... differential #diagnosis #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
fragmentation hemolysis ... hemolytic-uremic syndrome ... anemia" • HELLP syndrome ... differential #diagnosis #hematology ... #hemolysis
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH, Evans Syndrome ... , Drugs, Liver Disease ... Urobilinogen #Hemolysis ... Differential #Diagnosis #hematology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... and less common diseases ... diagnosis and treatment ... Vogt-Koyanagi-Harada (VKH) disease ... polychondritis • Behcet disease
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
in Autoimmune Hemolysis ... DAT Negative Hemolysis ... Cold agglutinin disease ... DAT #Autoimmune #Hemolysis ... #hematology #diagnosis
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... Wiskott-Aldrich syndrome ... and Autoimmune Diseases ... Antibody-mediated hemolysis ... Differential #Diagnosis #Hematology
End Stage Liver Disease (Cirrhosis) - Complications • Ascites • Esophageal Varices • Hepatic
End Stage Liver Disease ... Hepatopulmonary Syndrome ... • Hepatorenal Syndrom ... management #summary #hepatology
Hemoptysis - Differential Diagnosis Framework Airways: • Bronchitis • Bronchiectasis • Malignancy: Primary bronchogenic CA, Endobronchial
Hemoptysis - Differential ... Pneumonitis, GPA, Behcet syndrome ... Osler-Weber-Rendu syndrome ... • Valvular Disease ... Medicine @SCVMCMed #Hemoptysis
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