1063 results
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Heparin, Fondaparinux ... Anticoagulants - Pathophysiology ... Unfractionated heparin ... #Pharmacology #Pathophysiology ... #Heparins #LMWH
Pathogenesis of Edema in Hepatic Cirrhosis 

#Edema #Cirrhosis #Pathophysiology
Pathogenesis of Edema in Hepatic ... Edema #Cirrhosis #Pathophysiology
Hepatic Portal Venous System Drainage Anatomy
1) Most of the blood from abdominal organs goes into the
Hepatic Portal Venous ... goes into the hepatic ... capillaries of hepatic ... IVC using the hepatic ... System #Anatomy #Pathophysiology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Aldosterone Synthesis: Heparin ... #Hyperkalemia #Pathophysiology
Non-Cirrhotic Portal Fibrosis (NCPF) vs Extra-Hepatic Portal Vein Obstruction (EHPVO)

By Sharanya Kaushik @sharanyakaushik and Vallabh Shet
NCPF) vs Extra-Hepatic ... #NCPF #EHPVO #pathophysiology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Sequestrants → ↓ Hepatic ... Acid Pool → ↑ Hepatic ... sequestration #pathophysiology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced ... ♀, ↑Age, ESRD Pathophysiology ... • IgG binds heparin-PF4 ... • Start non-heparin ... of HIT #HIT #Heparin
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
aldosterone inhibition (Heparin ... differential #diagnosis #pathophysiology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
Mechanism of Action in Hepatic ... ammonia #hepatology #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... dysfunction (25%) • Hepatic ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin