20 results
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid ... swelling in w/ hereditary ... angioedema) • ... Hypersensitivity & anaphylaxis ... TXA #Tranexamic #Acid
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Acute allergic angioedema ... urticaria • Hereditary ... angioedema - Rare ... #Classification
Facial Swelling from Hereditary Angioedema on Physical Examination

19 year old Hereditary Angioedema (HAE) patient from Turkey.
Swelling from Hereditary ... Angioedema on Physical ... 19 year old Hereditary ... Angioedema (HAE ... #Angioedema #clinical
Stridor - Differential Diagnosis Framework:
High-pitched, variable respiratory sound

ETIOLOGIES:
Infectious:
 • Retropharyngeal abscess
 • Acute epiglottitis
 • Peritonsillar
Allergic/Immune: • Anaphylaxis ... • Hereditary ... angioedema Congenital ... malformations • Anaphylaxis ... Tracheal stenosis • Anaphylaxis
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
Clinical manifestations ... of anaphylaxis. ... doom. headache Angioedema ... incontinence #anaphylaxis
Causes of Angioedema: Differential Diagnosis Framework
Mast-cell mediated:
 • IgE dependent allergic reactions: Food, Drugs, Latex, Stings
Causes of Angioedema ... in arachidonic acid ... mediated: • ACEi • Hereditary ... inhibitor deficiency (hereditary ... angioedema) •
Antibiotic Classification by Mechanism of Action

Cell Wall Synthesis: 
Penicillins 
Cephalosporins 
Carbapenems 
Monobactams 
Beta-lactamase inhibitors
Glycopeptides 

 Protein
Antibiotic Classification ... Quinolones Folic Acid ... #Antibiotic #Classification ... Recommended Text: Clinical
Causes, classification and compensatory responses to shock.

Shock can be caused by any pathological process that leads
Causes, classification ... sepsis, burns and anaphylaxis ... shock is often clinically ... Causes #Types #Classification
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... Female predominance Anaphylaxis ... lesions - Wheals/angioedema
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of ... TLS: • Uric acid ... Calcium ≤ 7.0 mg/dL Clinical