19 results
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... urticaria • Hereditary ... • Bradykinin ... • Bradykinin-mediated ... #Classification
Angioedema - Diagnostic Algorithm

#Diagnosis #Allergy #Angioedema #Hereditary #Acquired #C1Inhibitor #Bradykinin #Algorithm
Angioedema - Diagnostic ... Diagnosis #Allergy #Angioedema ... #Hereditary #Acquired ... #C1Inhibitor #Bradykinin
Facial Swelling from Hereditary Angioedema on Physical Examination

19 year old Hereditary Angioedema (HAE) patient from Turkey.
Swelling from Hereditary ... Angioedema on Physical ... 19 year old Hereditary ... Angioedema (HAE ... #Angioedema #clinical
There are 2 Major Types of Angioedema:
 - Mast cell / histamine mediated – usually presents
Major Types of Angioedema ... presents with angioedema ... hypotension) - Bradykinin ... #Classification ... #Types #Bradykinin
Stridor - Differential Diagnosis Framework:
High-pitched, variable respiratory sound

ETIOLOGIES:
Infectious:
 • Retropharyngeal abscess
 • Acute epiglottitis
 • Peritonsillar
Allergic/Immune: • Anaphylaxis ... • Hereditary ... angioedema Congenital ... malformations • Anaphylaxis ... Tracheal stenosis • Anaphylaxis
Causes of Angioedema: Differential Diagnosis Framework
Mast-cell mediated:
 • IgE dependent allergic reactions: Food, Drugs, Latex, Stings
Causes of Angioedema ... NSAlDs, Aspirin Bradykinin ... mediated: • ACEi • Hereditary ... inhibitor deficiency (hereditary ... angioedema) •
Bradykinin-mediated Angioedema
Clinical features: Submucosal oedema (face, extremity, genitalia), Laryngeal dyspnea (25% of deaths), Recurrent attacks of
Bradykinin-mediated ... Angioedema Clinical ... pain Types: • Hereditary ... female, ACEI) Bradykinin ... #mediated #Angioedema
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
swelling in w/ hereditary ... angioedema) • ... Hypersensitivity & anaphylaxis
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
Clinical manifestations ... of anaphylaxis. ... doom. headache Angioedema ... incontinence #anaphylaxis
Causes, classification and compensatory responses to shock.

Shock can be caused by any pathological process that leads
Causes, classification ... sepsis, burns and anaphylaxis ... shock is often clinically ... Causes #Types #Classification