81 results
Stridor - Differential Diagnosis Framework:
High-pitched, variable respiratory sound

ETIOLOGIES:
Infectious:
 • Retropharyngeal abscess
 • Acute epiglottitis
 • Peritonsillar
Stridor - Differential ... Allergic/Immune: • Anaphylaxis ... • Hereditary ... angioedema Congenital ... stenosis #Stridor #differential
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
swelling in w/ hereditary ... angioedema) • ... Hypersensitivity & anaphylaxis ... #Pharmacology #hematology
Facial Swelling from Hereditary Angioedema on Physical Examination

19 year old Hereditary Angioedema (HAE) patient from Turkey.
Swelling from Hereditary ... Angioedema on Physical ... 19 year old Hereditary ... Angioedema (HAE ... #Angioedema #clinical
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
deposition disease, hereditary ... angioedema A - ... Mnemonic #diagnosis #differential ... #hematology
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
Clinical manifestations ... of anaphylaxis. ... doom. headache Angioedema ... incontinence #anaphylaxis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Intravascular Hemolysis - Differential ... Defects • Hereditary ... spherocytosis • Hereditary ... Extravascular #Differential ... Algorithm #Causes #Hematology
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
C3 ↓ C4 ↓↓ • Hereditary ... angiooedema C3 ... Levels #C3 #C4 #differential
An Algorithm for the Diagnosis of Wheezing and Stridor

Stridor: Louder, constant-pitch sound over central airways
Wheezing: Musical
Inflammatory: Anaphylaxis ... , Angioedema, Epiglottitis ... Asthma, COPD, Anaphylaxis ... Noisy #Breathing #differential
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Disorders • Hereditary ... Bleeding #Bruising #Differential ... Algorithm #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... membrane disorder (hereditary ... spherocytosis, hereditary ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology