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diagnosis allergy management differential acid airway anesthesia anesthesiology checklist classification cold hematology immunology indications intraoperative mediated pharmacology physicalexam pulmonary rheumatology
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
urticaria • Hereditary ... cell-mediated in > 90% of cases ... • Bradykinin ... Treatment of Angioedema ... • Bradykinin-mediated
Causes of Angioedema: Differential Diagnosis Framework Mast-cell mediated: • IgE dependent allergic reactions: Food, Drugs, Latex, Stings
Causes of Angioedema ... NSAlDs, Aspirin Bradykinin ... mediated: • ACEi • Hereditary ... inhibitor deficiency (hereditary ... Differential #Diagnosis #Causes
Stridor - Differential Diagnosis Framework: High-pitched, variable respiratory sound ETIOLOGIES: Infectious: • Retropharyngeal abscess • Acute epiglottitis • Peritonsillar
Allergic/Immune: • Anaphylaxis ... • Hereditary ... angioedema Congenital ... malformations • Anaphylaxis ... differential #diagnosis #causes
Tranexamic Acid - Indications and Pharmacology Pharmacokinetics: • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
swelling in w/ hereditary ... angioedema) • ... : Urine Common Uses ... rapid injection; Nausea ... Hypersensitivity & anaphylaxis
Bradykinin-mediated Angioedema Clinical features: Submucosal oedema (face, extremity, genitalia), Laryngeal dyspnea (25% of deaths), Recurrent attacks of
Angioedema Clinical ... pain Types: • Hereditary ... ineffectiveness • Specific treatment ... #mediated #Angioedema ... diagnosis #management #treatment
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia • Unexplained hypotension • Unexplained bronchospasm (wheeze may be absent
Intraoperative Anaphylaxis ... bradycardia • Angioedema ... arrest where other causes ... treatment pack ... require prolonged treatment
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... Female predominance Anaphylaxis ... lesions - Wheals/angioedema ... fever, fatigue, Nausea ... #rheumatology #comparison
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