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diagnosis differential clinical management algorithm causes hematology pathophysiology cardiology pulmonary workup pocus pharmacology anemia treatment nephrology microscopy physicalexam video comparison
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Diagnosis Algorithm Hereditary ... • Peripheral blood ... → Hereditary spherocytosis ... Immune mediated hemolysis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Microangiopathic Hemolytic ... drugs Elliptocyte: Hereditary ... Cold autoimmune hemolytic
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Spherocytes - Hereditary ... spherocytosis, Hemolytic ... Elliptocytes - Hereditary ... Schistocytes - Hemolytic
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
formation include hereditary ... spherocytosis and hemolytic ... Path #BloodSmear #Blood
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
• Metabolic/Hereditary ... Gilbert's syndrome • Hemolysis ... Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... intestines, white blood
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Inherited Non-hemolytic ... • Most common hereditary ... without evidence of hemolysis ... bilirubin in the blood
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... and RES-mediated hemolysis ... Defects • Hereditary ... spherocytosis • Hereditary ... Intravascular - Hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... Microangiopathic hemolytic ... purpura (TTP), Hemolytic ... defects (e.g. hereditary
Hemolytic Anemia - Hemolysis Diagnostic Workup Infographic by: Howard Ong #Hemolysis #Hemolytic #Anemia #Algorithm #MAHA #TTP #Diagnosis #Workup
Hemolytic Anemia ... - Hemolysis Diagnostic ... Howard Ong #Hemolysis ... #Hemolytic #Anemia
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... of anemia and hemolysis ... Immune-mediated Hemolysis ... • Autoimmune Hemolytic ... • Alloimmune Hemolytic
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