18 results
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
specificity - Falsely negative ... be negative if ... HLA-DQ8 - High negative ... Reflects response to treatment ... Tests #Diagnosis #Workup
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Causes of Culture Negative ... as a cause of a negative ... Sweet's Syndrome, hidradenitis ... Autoimmune: Crohn's disease ... Differential #Diagnosis #InfectiousDiseases
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
tests Test for celiac ... disease with serology ... endoscopy only if: • Negative ... Gastrointestinal #Evaluation #workup
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
fastidious gram-negative ... Culture & GS, PCR Treatment ... : • Severe Disease ... diagnosis #management #treatment ... #infectiousdiseases
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
hematology for workup ... Rebound effect from treatment ... Vasculitides, IBD, Celiac ... disease, Kawasaki
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
• Immunologic Workup ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Evolution: Chronic disease
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... • Some false negative ... with response to treatment ... IgG4 #Related #Disease ... management #phenotypes #workup
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
intermediate risk of disease ... because false-negative ... sample = 95% • A negative ... Testing #Diagnosis #Workup ... LatentTB #ActiveTB #InfectiousDiseases
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... microbiological techniques Work-up ... exists Infectious Diseases ... #differential #workup ... #infectiousdiseases
Coccidiomycosis - Diagnosis
Diagnosis:
 • Mildly elevated peripheral WBC, Eosinophilia (25%), Elevated ESR, Procalcitonin normal (95%)
 •
trend response to treatment ... Culture (ElA may be negative ... Coccidioides #Diagnosis #workup ... #infectiousdiseases