36 results
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
intermediate risk of disease ... (TST) False-negative ... because false-negative ... #Diagnosis #Workup ... LatentTB #ActiveTB #InfectiousDiseases
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
) - May be negative ... HLA-DQ8 - High negative ... Reflects response to treatment ... #Testing #Laboratory ... Tests #Diagnosis #Workup
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Causes of Culture Negative ... as a cause of a negative ... Sweet's Syndrome, hidradenitis ... Autoimmune: Crohn's disease ... Differential #Diagnosis #InfectiousDiseases
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
fastidious gram-negative ... photophobia, increased tearing ... Culture & GS, PCR Treatment ... : • Severe Disease ... #infectiousdiseases
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
spread of the Gram-negative ... susceptibility testing ... • Laboratory testing ... typically part of the workup ... #Microbiology #InfectiousDiseases
Gastroesophageal Reflux Disease (GERD) - Summary

GERD: Diagnosis
• Heartburn (substernal burning sensation) and acid regurgitation
• Chest pain
Extraesophageal
Gastroesophageal Reflux Disease ... cough GERD: Testing ... PPI failure + negative ... EGD Impedance testing ... Gastroesophageal #Reflux #Disease
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
Test for celiac disease ... Non-invasive testing ... endoscopy only if: • Negative ... Gastrointestinal #Evaluation #workup
Driving Impairment in Cirrhosis and Hepatic Encephalopathy 
 - Advise patients not to drive ~3 months
or optimize HE treatment ... withdraw/decrease sedative ... medications - Optimize treatment ... of comorbid diseases ... authorities for formal testing
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
• Immunologic Workup ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Evolution: Chronic disease
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... • Some false negative ... with response to treatment ... IgG4 #Related #Disease ... management #phenotypes #workup