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diagnosis management differential rheumatology microbiology testing arthritis endocarditis laboratory lupus summary table abscess active activetb aeromonas bcnie blastomycosis blood bloodculture
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... • Immunologic Workup ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Evolution: Chronic disease
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Causes of Culture Negative ... as a cause of a negative ... Sweet's Syndrome, hidradenitis ... Autoimmune: Crohn's disease ... Differential #Diagnosis #InfectiousDiseases
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Evolution: Chronic disease
Commonly Used Diagnostic Tests for Celiac Disease Tissue transglutaminase (tTG) IgA antibodies - Most reliable noninvasive test
specificity - Falsely negative ... ) - May be negative ... HLA-DQ8 - High negative ... Reflects response to treatment ... Tests #Diagnosis #Workup
Tularemia - Diagnosis and Management Summary Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection •
fastidious gram-negative ... Culture & GS, PCR Treatment ... : • Severe Disease ... diagnosis #management #treatment ... #infectiousdiseases
Capnocytophaga Pathogen: Capnocytophaga • 9 species, C. canimorsus responsible for the majority of infections • Gram-negative rod,
infections • Gram-negative ... ), Malignancy, SLE ... fusiform gram-negative ... Treatment: • 50% ... microbiology #zoonotic #infectiousdiseases
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
microbiological techniques Work-up ... See charts - ... exists Infectious Diseases ... #differential #workup ... #infectiousdiseases
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... • Some false negative ... with response to treatment ... IgG4 #Related #Disease ... management #phenotypes #workup
Tuberculosis Testing LATENT TB • LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
intermediate risk of disease ... because false-negative ... sample = 95% • A negative ... Testing #Diagnosis #Workup ... LatentTB #ActiveTB #InfectiousDiseases
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
cell carcinoma (native ... , Busulfan • Disease ... Goodpasture's syndrome, SLE ... urine #management #treatment
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