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diagnosis differential management clinical pharmacology algorithm pathophysiology causes dermatology allergy photo hematology classification table comparison treatment medications physicalexam transfusion syndrome
Pressor area 1a Neuronal Sympathetic tonus t Vessel stretch Myogenic reaction 2a local Port Endothelin-1 1 (ETA) PGF2a, thromboxane Constriction ADH (V1), epinephrine (a1), angiotensin lI За Hormonal 1b Neuronal Sympathetic tonus Dilation Parasympathetic system (salivary glands,
stretch Myogenic reaction ... Bradykinin, 4 kallidin ... Acetylcholine (M), АТР, #histamine
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
cells- contain histamine ... during an allergic reaction ... Or Inflammatory Reactions
Sleep Regulation of sleep is critical for life! Ever wonder why you can’t fall asleep while hungry
hungry or why anti-histamines ... #Sleep #anti-histamine
Drug-Induced Edema Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
which include: - Bradykinin ... permeability) - Histamine
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Non-allergic drug reaction ... • Bradykinin ... angioedema • Bradykinin-mediated
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... degranulation releasing histamine ... Acute transfusion reaction ... hypersensitivity #reactions
Pathophysiology of ACE inhibitor-induced angioedema: Angioedema is a vascular reaction associated with tissue (subcutaneous, submucosal) edema
is a vascular reaction ... angioedema are bradykinin ... Allergy #Kininogen #Bradykinin
There are 2 Major Types of Angioedema: - Mast cell / histamine mediated – usually presents
- Mast cell / histamine ... hypotension) - Bradykinin ... Classification #Types #Bradykinin
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
hypersensitivity reaction ... mediators => • Histamine
Effects of H1 Antihistamines at Histamine, Adrenergic, Cholinergic, and Serotonin-Binding Receptors Cholinergic - Incr Dry mouth, Incr
Antihistamines at Histamine ... Incr Appetite Histamine
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