11 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... - Arthralgia, Arthritis ... #Lupus #Erythematosus ... #SLE #MSK #Musculoskeletal ... pathophysiology #signs
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
50%): Pleurisy / effusion ... of hip (rare), Arthritis ... #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
“Bamboo Spine” Fusion ... • Psoriatic arthritis ... Lupus - with Systemic ... Lupus Erythematosus ... Joint #Disorders #msk
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Classification Criteria for Systemic ... Lupus Erythematosus ... cutaneous lupus • Arthritis ... or pericardial effusion ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... SLE) - Typical Signs ... , Arthralgia / arthritis ... #Lupus #Erythematosus ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... #Lupus #Erythematosus ... autoantibodies #signs ... #differential #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... Lungs: • Pleural effusions ... Neuropsychiatric systemic ... #Diagnosis #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
suggested by warmth, effusion ... noninflammatory Signs ... - Autoimmune Rheumatologic ... Differential #Diagnosis #MSK ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and often causes arthritis ... ischemia - Skin: erythematous ... lupus erythematosus ... purpura: strong sign ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... GCA (Giant Cell Arteritis ... ischemia • Skin: Erythematous ... and often causes arthritis ... Differential #Diagnosis #Rheumatology