42 results
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Clinical Manifestations ... of Systemic Lupus ... Manifestations #Signs ... #Symptoms #Rheumatology ... #Diagnosis
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin thickening Signs ... and Symptoms: ... #diagnosis #signs ... #symptoms #testing ... #workup
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... organ-specific signs ... or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
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Pathogenesis and Clinical ... sensory • Before diagnosis ... MeralgiaParesthetica #MSK ... pathophysiology #differential ... #diagnosis #signs
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
• CNS symptoms ... thin smear • Signs ... node biopsy • Clinical ... values supporting hematologic ... #diagnosis
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
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Systemic Lupus Erythematosus ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
the lymphatic system ... renal failure Clinical ... anterior/posterior MSK ... 5-10%, nervous system ... #Management #Signs
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
central nervous system ... Multiple Sclerosis Diagnosis ... Signs and symptoms ... patients with clinically ... stimulation Clinical
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... with lymphatic system ... pattern of spread, B symptoms ... Amy Chung, MD, MSc ... pathophysiology #Hematology