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diagnosis oncology workup eosinophils hes hypereosinophilia pancytopenia causes chronic cll eosinophil hypereosinophilic leukemia lymphocytic mds myelodysplasia myelodysplastic platelets syndromes thrombocytosis
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #eosinophilia # ... #management #algorithm
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... glucocorticoid treatment ... #Disorders #Algorithm ... #Differential # ... diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... Secondary Causes: - Allergic ... #diagnosis #hematology ... #differential # ... management #eosinophils
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Diagnosis Algorithm ... Consumption Disorders ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Diagnosis Algorithm ... Consumption Disorders ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... anemia Treatment ... #hematology #diagnosis ... #management
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... hypertension and/or drug treatment ... Megaloblastic anemia-rare ... white blood cell aplasia ... diagnosis #causes #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... • Aplastic Anemia ... Myeloproliferative Disease • Neutropenia ... blood count with differential ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Cytopenias: • Neutropenia ... , anemia, thrombocytopenia ... Pure red cell aplasia ... microglobulin Treatment ... workup #oncology #hematology
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