17 results
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - ... Elevated PTH (High ... Hypocalciuric Hypercalcemia ... Low PTH: • Elevated ... Thiazides/Lithium #Hypercalcemia
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Hypercalcemia Evaluation ... PTH - Frankly high ... FeCa <1 %) - Low ... BrighamChiefs #Hypercalcemia ... #workup #differential
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... magnesium, and calcium ... patients sensitive to high ... Potassium #Binding #Hyperkalemia ... #pharmacology #table
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
abnormalities - Hypercalcemia ... #Diagnosis #Low ... #Magnesium #Table ... #Classification ... #Causes #Workup
Types of Renal Calculi

Calcium oxalate
 - Interstitial apatite plaque, Low urine volume, Increased urinary calcium excretion,
hypercalciuria, Hypercalcemia ... hypercalciuria, Hypercalcemia ... Mycoplasma infections, High ... Renal #stones #differential ... #diagnosis #causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... • LDH ↑ • Hyperkalemia ... /Late - Hypercalcemia ... potassium and calcium ... Dialysis for severe hyperkalemia
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... WBC count cause ... , Elevated Cr, Low ... hydration - Hyperkalemia ... phos binders
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pump - Digoxin works ... causes: - Increased ... - Hyperkalemia ( ... high potassium levels ... (or low potassium
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Is Dangerous in Hyperkalemia ... shift • Saline Causes ... densa receives high ... decreased renal blood flow ... • Saline May Cause
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... acidosis) • Low ... emcrit.org/ibcc/hyperkalemia ... management of hyperkalemia ... #Hyperkalemia