84 results
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... calcium)-alkali syndrome ... #Causes #differential ... calcium #high #endocrinology
Causes of Hypercalcemia

#Differential #Hypercalcemia #Diagnosis #Causes #Endocrinology
Causes of Hypercalcemia ... #Differential ... #Hypercalcemia ... #Diagnosis #Causes ... #Endocrinology
Causes of Hypercalcemia - Differential Diagnosis Algorithm
 • Primary Hyperparathyroidism 
 • Possible Familial Hypocalciuric Hypercalcemia
Causes of Hypercalcemia ... Hypocalciuric Hypercalcemia ... • Humoral Hypercalcemia ... DTomacruzM #Hypercalcemia ... #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - ... Hypocalciuric Hypercalcemia ... Low PTH: • Elevated ... Thiazides/Lithium #Hypercalcemia ... #endocrinology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... -> Uric Acid (low ... Urate Nephropathy (low ... • Hyperkalemia
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Hypomagnesemia - Differential ... Familial: Bartter syndrome ... and Gitelman syndrome ... pentamidine), Hypercalcemia ... nephrology #magnesium #low
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Hypocalciuric Hypercalcemia ... calcitriol induced hypercalcemia ... Infantile idiopathic hypercalcemia ... @aishaikh #Hypercalcemia
Multiple Endocrine Neoplasias (MEN syndromes) 

MEN I
• Hyperparathyroidism 
• Hypercalcemia 
• Possible ZE syndrome 
• Various
Neoplasias (MEN syndromes ... Hyperparathyroidism • Hypercalcemia ... Hyperparathyroidism • Hypercalcemia ... MultipleEndocrineNeoplasia #Differential ... #Endocrinology
Hypercalcemia - EKG Findings
Causes of Hypercalcemia 
• Malignancy 
• Milk-alkali syndrome 
• Vitamin D toxicity 
•
Hypercalcemia - ... of Hypercalcemia ... • Milk-alkali syndrome ... Thiazide diuretics #Hypercalcemia ... Electrocardiogram #Differential
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential ... other hormonal causes ... uw_IMresidency #Hypercalcemia ... Diagnosis #algorithm #endocrinology