32 results
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... Determine whether PTH-dependent ... uw_IMresidency #Hypercalcemia ... #Workup #Differential ... #calcium
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... hyperparathyroidism, Malignancy ... #Causes #differential ... #high #endocrinology
Diagnostic algorithm for the workup of hypercalcemia. The diagnostic workup for patients presenting with hypercalcemia rests
of hypercalcemia ... presenting with hypercalcemia ... hypocalciuric hypercalcemia ... #Diagnosis #Hypercalcemia ... #Workup #Differential
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
Hypercalcemia - ... Hyperparathyroidism • Hypercalcemia ... Hypocalciuria Hypercalcemia ... • PTH-Related ... Paget's Disease #Hypercalcemia
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Hypocalciuric Hypercalcemia ... PTHrP: Malignancy ... calcitriol induced hypercalcemia ... @aishaikh #Hypercalcemia
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - ... Hypocalciuric Hypercalcemia ... Bony Mets - Calcium ... Thiazides/Lithium #Hypercalcemia ... Algorithm #causes #endocrinology
Mechanism of malignancy-associated hypercalcemia. Abbreviations: 1,25(OH)2D, 1,25-dihydroxyvitamin D; NHL, non-Hodgkin lymphoma; PTH, parathyroid hormone; PTHrP, PTH-related
hypercalcemia. ... non-Hodgkin lymphoma; PTH ... Pathophys #Diagnosis #Hypercalcemia ... #Malignancy #Mechanism ... #Frequency #Differential
Hypercalcemia Diagnosis Algorithm
 - Primary Hyperparathyroidism
 - FHH
 - Hypercalcemia of malignancy
 - Local osteolytic hypercalcemia
Hypercalcemia Diagnosis ... Hyperparathyroidism - FHH - Hypercalcemia ... Local osteolytic hypercalcemia ... edgarvlermamd #Hypercalcemia ... #differential
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Hypercalcemia Evaluation ... 2) PTH - Frankly ... BrighamChiefs #Hypercalcemia ... #workup #differential ... #calcium #elevated
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
Parathyroid Hormone (PTH ... ) Effect in Calcium ... - Net Effect Hypercalcemia ... Parathyroid #Hormone #PTH ... pathophysiology #endocrinology