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diagnosis nephrology table algorithm management calcium aki cancer high hypertension injury kidney neurology oncology secondary acromegaly cardiology chronic diabetes diuresis
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... Immobilization Hypercalcemia ... intoxication #Hypercalcemia ... #Causes #differential
Hypercalcemia Workup and Differential Diagnosis Framework 1) Determine whether PTH-dependent 2) Assess for other hormonal causes 3) Assess for
Hypercalcemia Workup ... and Differential ... uw_IMresidency #Hypercalcemia ... #Workup #Differential ... Diagnosis #algorithm #endocrinology
Multiple Endocrine Neoplasias (MEN syndromes) MEN I • Hyperparathyroidism • Hypercalcemia • Possible ZE syndrome • Various
Hyperparathyroidism • Hypercalcemia ... Hyperparathyroidism • Hypercalcemia ... MultipleEndocrineNeoplasia #Differential ... #Endocrinology ... #Classification
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia Focal Hyporeflexia: • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Polyneuropathy, Acute ... stroke, Acute spinal ... Hyporeflexia: • Hypercalcemia ... Hyperreflexia: • Hypocalcemia ... #differential #
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... Renal failure, acute ... Jansen disease #Hypercalcemia ... #Causes #Differential
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 Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
abnormalities - Hypercalcemia ... - Hypokalemia ... Hypomagnesemia #Differential ... Magnesium #Table #Classification ... #Causes #Workup
Causes of Hypercalcemia due to increased Vitamin D levels • The BIG 3:
Causes of Hypercalcemia ... Crohn's disease, Acute ... Genetic: Williams syndrome ... jamiekwillows #Hypercalcemia ... #differential #
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
Hypercalcemia Evaluation ... 1) Clinical clues ... BrighamChiefs #Hypercalcemia ... #workup #differential ... #diagnosis #endocrinology
Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... • Milk-alkali syndrome ... #Hypercalcemia ... #Causes #endocrinology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Distributive Shock, HRS, Hypercalcemia ... Artery Stenosis, Abdominal ... Compartment Syndrome ... Diagnosis #nephrology #causes
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