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diagnosis algorithm differential neurology pharmacology rheumatology table amiodarone apml capillary cardiology cerebritis chf clarksons clinical cns differentiation disease diuresis diuretics
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... hydration - Hyperkalemia ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
• Obstructive: Pulmonary ... Abdominal compartment syndrome ... ) UOP > 0.5 cc/kg ... Differential #Diagnosis #criticalcare ... #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Lumbar Puncture, EEG ... #rheumatology # ... cerebritis #diagnosis #management ... #treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Prednisone 5mg/kg ... Imaging: CXR- pulmonary ... APML #diagnosis #management ... #hematology #oncology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... acute coronary syndrome ... differential #algorithm #management ... #table #foamed ... heartfailure #chf #criticalcare
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Blood transfusion, Hypercalcemia ... epilepticus Treatment ... underlying cause • Treatment ... #diagnosis #management ... #neurology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
irrigation • Management ... Torsemide) • Acute pulmonary ... Hyponatremia • Hypercalcemia ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
starting amiodarone treatment ... respiratory distress syndrome ... of lipid-laden 'foamy ... macrophages Treatment ... #diagnosis #management
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... filling +++ (risk of pulmonary ... ) • IVIg 2 g/kg ... #diagnosis #management ... #rheumatology
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