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Drug-induced renal disorders - The most commonly used nephrotoxic drugs

#Pharmacology #Nephrotoxicity #Drugs #Medications #Most #Common #DrugInduced
Drug-induced renal ... #Medications #Most ... #DrugInduced #Acute ... #KidneyInjury #AKI ... #Table #List
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Distributive Shock, HRS, Hypercalcemia ... Compartment Syndrome, Medications ... Pigment, Protein) • AIN
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing ... Acute Kidney Injury ... (AKI) Prerenal: ... , tenofovir • AIN ... #Injury #Medications
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
are usually the drugs ... e.g. at lower doses ... pharmacology #comparison #treatment ... #medications #dosing ... #drugs #table #
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for ... goals of acute ... Indications for ... medications used ... #Management #Medications
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
Acute dystonia ... • Tx: Reduce dose ... greatest risk • Tx: Dose ... reduction; change medication ... #Medications #SideEffects
Acute Kidney Injury (AKI) - Management Principles
Prerenal - Correct hemodynamic derangements:
 • If low preload →
Acute Kidney Injury ... (AKI) - Management ... • AIN → Consider ... Foley catheter • Medications ... #Acute #Kidney
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Toxins - Drugs ... symptoms: - Muscle pain ... - Abdominal pain ... declines > ALT) • AKI ... + myoglobin AKI
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... information (e.g. dose ... duration), Several medications ... /HDS treatments ... dechallenge • Acute
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... , RTA Type IV, AI ... Elimination (see Table ... STOP offending medications ... Transient, repeat dose