995 results
Generalized Hyperpigmentation Differentials
Use the Mnemonic "no skin SPARED"

Images from dermnet.nz and merckmanuals

Mnemonic from https://www.medscape.com/slideshow/dermatology-mnemonics-6011359#5 #diagnosis #differential
Generalized Hyperpigmentation ... #differential #symptoms
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
disorders: - Hyperpigmentation ... nervous system symptoms ... Headache, visual symptoms ... Insufficiency #Signs #Symptoms
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
Deficiency - Signs and Symptoms ... failure • Skin: Hyperpigmentation ... Deficiency #Signs #Symptoms
Symptoms and Signs of Hypocalcemia
Muscular: Weakness, fatigue, Spasms, cramps
Neurologic: Tetany, Chvostek sign, Trousseau sign, Circumoral and
Symptoms and Signs ... Dermatologic: Hyperpigmentation ... #Hypocalcemia #Symptoms
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
ketoconazole, etomidate) Symptoms ... pain (10-40%), hyperpigmentation ... Hyperpigmentation
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Pigmentations - Hypopigmentation ... and Hyperpigmentation ... HYPERPIGMENTATION ... #Hypopigmentation ... #Hyperpigmentation
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Cortisol Deficiency: Symptoms ... Deficiency: Signs • Hyperpigmentation ... Androgens: • Symptoms ... physical: - Symptoms ... diagnosis #signs #symptoms
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
of the systemic symptoms ... bleeding, or other symptoms ... that desquamate → hypopigmentation ... → hyperpigmentation
Adrenal Crisis
Do not confuse acute adrenal crisis with Addison disease. In 1855, Thomas Addison described a
weight loss, and hyperpigmentation ... as the primary symptoms
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
PBC Signs and Symptoms ... Examination: • Skin hyperpigmentation