10 results
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Amyotrophic Lateral ... examination finding of amyotrophy ... lateral sclerosis Pathophysiology ... diagnosis column Treatment ... #Sclerosis #neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
present, symptoms, signs ... symptoms (same as ... aquagenic pruritis"), Hypertension ... : • As with ET ... #hematology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... lidocaine, +/- pre-treatment ... reduces ICP (but also ... raise ICP • Hypertension ... #neurology #neurosurgery
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... Puncture, EEG Treatment ... (for secondary APS ... #rheumatology # ... diagnosis #management #treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... edema visualized as ... epilepticus Treatment ... underlying cause • Treatment ... diagnosis #management #neurology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
- Gitelman SIGNS ... Muscle weakness • Hypotension ... • AMS (altered ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Scleroderma Renal ... Abrupt onset of hypertension ... anemia (MAHA) Pathophysiology ... Renal #Crisis #rheumatology ... #nephrology #diagnosis
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... • Portal hypertension ... Treatment Overview ... be substituted as ... Syndrome #Hepatology #Nephrology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
• In all patients ... Presentation • Common Signs ... Pathophysiology ... Treatment Approach ... Diagnosis #Management #Hematology