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diagnosis differential nephrology rheumatology glomerular glomerulonephritis hematology hyponatremia lupus management sle table acute aki antiphospholipid apls ascites blood comparison different
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus Nephritis ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Algorithm INDICATIONS ... evaluation or workup ... 1,500 cells/µL Workup ... for secondary causes ... eosinophilia (common causes
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... infections are common causes ... #glomerular #testing ... #workup #diagnosis
Hypereosinophilia Different Diagnosis and Workup Secondary causes are broad so start with a med review, the most
Diagnosis and Workup ... Secondary causes ... the most common cause ... the US inpatient setting ... #algorithm
Suggested diagnostic approach to a patient with exudative ascites. Low ascitic fluid protein should direct practitioners
syndrome as a cause ... Although nonhepatic causes ... obstruction, nephrotic ... ascites #diagnosis #workup ... #algorithm #differential
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... and Diagnosis Algorithm ... mimics, repeat testing ... Nephrology if cause ... #Workup #urology
Causes of Hyponatremia - Differential Diagnosis Algorithm Hypovolemia, UNa > 20: • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Differential Diagnosis Algorithm ... Cerebral salt wasting ... , UNa < 20 • Nephrotic ... #Causes #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Algorithm and Differential ... osmolarity If cause ... • Interstitial nephritis ... #Injury #AKI #Workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
ulcers, Lupus nephritis ... • Immunologic Workup ... Positive in 60-80% of cases ... 80% - Low complement
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... 90% - Low complement ... ulcers, Lupus nephritis ... • Immunologic Workup ... 80% - Low complement
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