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differential rheumatology dermatology management skinrash anemia comparison lupus physicalexam sle ulcerative ulcers approach bleeding bruising champs clinical clinicopathology compared cryoglobulinemia
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology # ... classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
Vascular Skin Lesions - Differential Diagnosis Algorithm - Petechiae < 0.2 cm diameter - Purpura 0.2
- Differential Diagnosis ... Algorithm - Petechiae ... #SkinRash #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... HUS • DIC • Vasculitis ... #Algorithm #Causes ... #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential Diagnosis ... perfringens - Complement-Mediated ... #Algorithm #Causes ... #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... • Steroids • Vasculitis ... #Algorithm #Causes ... #Hematology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
- Differential Diagnosis ... Algorithm Physical ... insufficiency • Vasculitis ... • Bleomycin Hematologic ... #Algorithm #causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... #types #classification ... #rheumatology #
Skin Ulcers of the Lower Legs / Feet - Differential Diagnosis Algorithm Physical: • Pressure • Trauma • Radiation Vascular: • Arterial
- Differential Diagnosis ... Algorithm Physical ... insufficiency • Vasculitis ... ulcerative #skinrash #dermatology ... #Algorithm #causes
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