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diagnosis differential rheumatology causes sle systemic table types allergy alopecia comparison dermatology hairloss hematology hypersensitivity nephritis nephrology reactions vasculitis champs
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... Erythematosus ( ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus ... anticoagulant • Complement ... #EULARACR #Classification ... #Erythematosus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... pneumonitis • Diffuse ... enteropathy, and diffuse ... RNP antibodies, Complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... , oral ulcers, Lupus ... 80% - Low complement ... #Systemic #Erythematosus
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... Irreversible-biopsy required • Lupus ... erythematosus ... • Discoid lupus ... erythematosus
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... • Systemic Lupus ... Erythematosus ... Hodgkin's Lymphoma #Diffuse
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... Proliferative Class IV - Diffuse ... DrFlashHeart #Lupus ... Nephritis #SLE #Classification ... differential #diagnosis #management
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... severity (ISN/RPS classification ... by 12 months Classification ... • Class IV - Diffuse ... glomeruli) Diffuse
Causes of Hemoptysis - Differential Diagnosis Algorithm Massive Hemoptysis (>I00 mL in 24 hours) • Malignancy •
Differential Diagnosis Algorithm ... • Bronchitis Diffuse ... Vasculitis • Lupus ... Erythematosus ... Differential #Diagnosis #Algorithm
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... Erythematosus ( ... 80% - Low complement ... Usual therapeutic management ... rheumatology #diagnosis #management
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