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diagnosis rheumatology erythematosus differential management systemic causes criteria dermatology hairloss vasculitis comparison cryoglobulinemia cryoglobulins druginduced eularacr focal nephritis nephrology slicc
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... : Non-scarring alopecia ... pericarditis • Hematologic ... anticoagulant • Complement ... #Criteria #SLE
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... Irreversible-biopsy required • Lupus ... • Discoid lupus ... #dermatology #Differential ... #Diagnosis #Algorithm
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Photosensitivity, Alopecia ... , oral ulcers, Lupus ... 80% - Low complement ... Management #Summary #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... - NON-SCARRING ALOPECIA ... anticoagulant - Low complement ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... Skin Disease Classification ... and permanent alopecia ... pneumonitis • Diffuse
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... Erythematosus (SLE ... Photosensitivity, Alopecia ... 80% - Low complement ... #table #rheumatology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... severity (ISN/RPS classification ... by 12 months Classification ... • Class IV - Diffuse ... glomeruli) Diffuse
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required • Lupus erythematosus • Lichen
Diffuse Hair Loss ... Diagnosis Algorithm ... Irreversible-biopsy required • Lupus ... #dermatology #Differential ... #Diagnosis #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... vasculitis, and SLE ... #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Low serum C4 complement ... (e.g. systemic lupus ... erythematosus (SLE ... diagnosis #types #classification ... #rheumatology #
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